Healthy metabolic ageing

Healthy metabolic ageing

Fiit-ns® is a combination of plant extracts and vitamin B3 active on the maintenance of the ageing markers of the metabolism and contributes to the improvement of the feeling of well-being and energy. The holistic action of Fiit-ns® confers an improved quality of life. Supported by 2 clinical trials and a consumer test on 200 participants. 900 mg/day.

Fiit-ns® - Key features

  • Proven synergy of natural bioactives and vitamin B3
  • Improves markers of ageing
  • Increases vitality and energy
  • Supports engagement in higher levels of activities
  • Promotes a better quality of life
  • Formulated with vitamin B3, supported with an EU approved claim

Science supporting Fiit-ns®

Two clinical studies have been run on Fiit-ns®. Both studies were conducted according to double-blind, randomized, and placebo-controlled protocols.

A consumer test, run on 200 people, highlights the perceived changes on quality of life, energy, overwell wellbeing and associated benefits following the consumption of Fiit-ns®.


Fiit-ns® provides 4 complementary subclasses of polyphenols within the flavonoid category: flavanols, flavanones, procyanidins and anthocyanins. 
Fiit-ns® combines polyphenols from grapefruit, grape, green tea and black carrot with vitamin B3 and low-dose caffeine.

Primary active compounds
     Flavonoids               ≥ 15%

Secondary active compounds
     Caffeine                  45 mg
     Vitamin B3              16 mg

Composition: Green tea extract (Camellia sinensis (L.) Kuntze), Guarana seed extract (Paullinia cupana Kunth), Grape extracts (Vitis vinifera L.), Grapefruit extract (Citrus paradisi Macfad), Black carrot extract (Daucus carota L.).

Recommended daily dosage: 900 mg

Mechanism of action

Fiit-ns® activates the virtuous circle.

"Quality of life (QOL) is defined as the degree to which an individual is healthy, comfortable and able to participate in and enjoy life events. It’s more than just the absence of disease: it’s a state of complete physical, mental and social well-being." according to the World Health Organization.

Polyphenols are bioactive compounds demonstrated to help the body rebalance metabolic functions

The combined action of polyphenols from grapefruit, grape, green tea and black carrot, with vitamin B3 and low-dose caffeine helps to (re)activate a virtuous circle to reach a better quality of life.

Fiit-ns® is clinically proven to support healthy metabolic ageing for an enhanced quality of life. Vitamin B3 in Fiit-ns® contributes to increase the feeling of energy while reducing tiredness engendered by active lifestyles.

Fiit-ns® makes healthy ageing possible and targets any age group.

Clinically supported benefits

Two clinical studies have been run on Fiit-ns®.
Both studies were conducted according to double-blind, randomised, and placebo-controlled protocols.


Paris, France
American Hospital

Madrid, Spain
UCAM, University of Murcia


12 weeks

16 weeks


17 subjects
BMI: 30-33 kg/m2
Age: 39-45 years old

72 subjects
BMI: 25-38 kg/m2
Age: 26-52 years old


Physical activity
30 min/week

Normo-caloric diet
(Harris and Benedict)

Body composition
ViScan (Tanita corporation)

Physical activity
Usual level, Recorded

Normo-caloric diet
(Harris and Benedict)

Body composition
DXA scan

2 x 450 mg/day
2 x 450 mg/day

Fiit-ns® improves metabolic function.





Fiit-ns® supplementation contributes to a significant improvement of metabolic markers:

  • Lipid profile: significant reduction of triglyceride level (-14%) within 3 months and significant improvement of the HDL-c to LDL-c balance.
  • Glycemia: significant impact on pre-diabetes markers with a reduction in fasting glycemia (5.7%) and reduction of glycated hemoglobin (13.6%).
  • Oxidative status: significant increase in the level of endogenous superoxide dismutase (30.5%) and reduction in malondialdehyde level (34%).
  • Low-grade inflammation: significant reduction in fibrinogen and high-sensitivity C-reactive protein, the hepatic marker of inflammation.

Fiit-ns® improves body composition.


Supplementation with Fiit-ns® helps to improve body composition.

The index of central obesity (ICO), measured by the ratio of waist circumference to height, is significantly improved; 83% of the fat loss is from the trunk area during the supplementation.

Fiit-ns® provides higher vitality.

The International Physical Activity Questionnaire (IPAQ) assesses total physical activity within 4 life domains:

  • Working
  • Transportation
  • Housework and gardening
  • Leisure time


The score established in MET-min (Metabolic Equivalent = energy cost of physical activity) represents the level of activity of the subjects measured per week.

Subjects taking Fiit-ns® are involved in more physical activities than the placebo group.

Fiit-ns® improves health-related quality of life.

Overall quality of life of the subjects has been measured with the international referential SF-36. This questionnaire introduces 36 questions classified in 8 domains that describe physical and mental health.

Physical functioning           
Role limitations (physical)
Bodily pain
General health
Role limitations (emotional)
Social functioning
Emotional well-being

Fiit-ns® is safe.

No adverse event linked to Fiit-ns® supplementation over the period 2008-2023 has been recorded.

Regulatory & Certifications

Non-GMO, Halal, gluten-free, suitable for vegans

Vitamin B3 in Fiit-ns® contributes to normal energy-yielding metabolism.*


Cases J. et al., Int. J. Food Sci. Nutr., 2015, 66 (1): 120-125
Romain C. et al., Nutrients, 2021

*Regulation 432/2012; EFSA Journal; 2010, 8 (10): 1757

This website is intended to provide information about Fytexia’s ingredients, used in various food/dietary supplement products around the world. It is only intended for business to business and to provide information to food/dietary supplement professionals and is not designed for the general public. Statements used on this website have not been evaluated by the Food and Drug Administration or any other competent authority. Products are not intended to diagnose, treat, cure or prevent any disease.